ON-DEMAND WEBINAR
Scale Up Your Screening:
Integrating Automation Into 3D Biology for Therapeutic Drug Discovery
High-throughput screening of 3D cell models, such as patient-derived organoids (PDOs), comes with a unique set of challenges when it comes to reproducibility, cost, and scalability.
By implementing an end-to-end, automated workflow, labs can lower cost, simplify protocols, and scale-up assay screenings. Listen in as experts share how to standardize and scale up organoid production, culture maintenance, and therapeutic and disease model assessment. They focus on different solutions to common researcher pain points in the 3D biology experimental pipeline, including:
- Bioproduction and manufacturing process for PDOs
- The benefits of scaling organoid production
- How to overcome the challenges of growing and treating organoids
- Robotic integrations – key for saving time and resources for 3D culture maintenance
- High-content imaging – critical for testing therapeutic targets and disease challenges in fixed and live organoid and spheroid models
Learn more about the systems behind the methods:
ImageXpress Confocal HT.ai system
Powerful multi-laser light sources, a deep tissue penetrating confocal disk module, water immersion objectives and modern machine learning analysis software
- Ideal for highly-complex cell-based and 3D assays
- Seven-channel high-intensity lasers generating brighter images with higher signal-to-background
- Spinning confocal disk technology for deeper tissue penetration, resulting in sharper images with improved resolution
- Water immersion objectives offering quadruple the signal at lower exposure times for greater sensitivity and image clarity without sacrificing speed
- Optional IN Carta software, leveraging intuitive, modern machine learning
MetaXpress software for ImageXpress high-content imaging systems
Multi-level analysis tools for a wide range of applications
- Meet high throughput requirements with a scalable, streamlined workflow
- Adapt your analysis tools to tackle your toughest problems, including 3D analysis
- Schedule automatic data transfer between third-party hardware sources and secure database
- Set up hundreds of routinely used HCS assays using MetaXpress software modules
- Export data to IN Carta software, leveraging intuitive, modern machine learning
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